反应详情

Following the procedure of Example 54, but substituting allyl bromide for iodopropane and 5 -(amino)-5,6-dihydro-4H-imidazo [4,5,1 -i j]quinolin-2(1H)-one for 6-bromo-1,2,3, 4-tetrahydro-8-nitro-3-quinolinamine dihydrochloride there were obtained 5-(diallylamino)-5, 6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one, mp 150-152 from ethyl acetate and 5-(allyl-amino)-5,6-dihydro-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one. The latter compound was converted to the hydrochloride salt, mp 260° C. from methanol:ether.