3,4-dihydro-2H-pyran → 2-(3-Butynyloxy)tetrahydro-2H-pyran

HRID 1648420Notes

Reaction equation

HRID 1648420 reaction equation
[CH3:1][CH:2](O)[C:3]#[CH:4].[O:6]1[CH:11]=[CH:10][CH2:9][CH2:8][CH2:7]1.[OH-:12].[Na+]>Cl>[O:12]1[CH2:7][CH2:8][CH2:9][CH2:10][CH:11]1[O:6][CH2:4][CH2:3][C:2]#[CH:1]

Participants

5

Reactant 3

HCID 80803,4-dihydro-2H-pyranHCID 14798Sodium HydroxideHCID 162393-Butyn-2-ol

Product 1

HCID 1424402-(3-Butynyloxy)tetrahydro-2H-pyran

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidCatalyst

Procedure

3-Butyn-2-ol (1 mol) and dihydropyran (1.1 mol) are mixed and 2 drops of concentrated hydrochloric acid are added. The reaction mixture is allowed to stand 2 to 3 hours at room temperature and a few pellets of sodium hydroxide are added. After filtration, the product is distilled.

Workup

  1. filtrationAfter filtration
  2. distillationthe product is distilled

Sources & evidence

ORD record
ord-201a851f752244b1af09ff9689fe6d6b
Source dataset
uspto-grants-1995_07
Patent number
US05436273

Reaction notes

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