Benzoyl chloride → 120067-47-2

HRID 1649733Notes

Reaction equation

HRID 1649733 reaction equation
[NH:1]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH2:5][CH2:4][C:2]1=[O:3].[C:12](Cl)(=[O:19])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1.[Cl-].[Al+3].[Cl-].[Cl-]>C(=S)=S>[C:12]([C:8]1[CH:7]=[C:6]2[C:11](=[CH:10][CH:9]=1)[NH:1][C:2](=[O:3])[CH2:4][CH2:5]2)(=[O:19])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

5

Reactant 3

HCID 7412Benzoyl chlorideHCID 64796HydrocarbostyrilHCID 6451240Aluminum(III) Chloride

Product 1

HCID 14373255120067-47-2

Reagents, catalysts & solvents 1

HCID 6348Carbon DisulfideSolvent

Procedure

A mixture of 2.2 g of 3,4-dihydrocarbostyril, 3.21 g of benzoyl chloride and 13 g of aluminum chloride in 50 ml of carbon disulfide was refluxed for 2 days. The reaction mixture was poured onto ice water and the resulting solid filtered off, washed with water and dried under reduced pressure to yield 6-benzoyl-3,4-dihydrocarbostyril, m.p. 205°-207° C.

Workup

  1. temperaturewas refluxed for 2 days
  2. additionThe reaction mixture was poured onto ice water
  3. filtrationthe resulting solid filtered off
  4. washwashed with water
  5. customdried under reduced pressure

Sources & evidence

ORD record
ord-e27d9f1b58714320bc123bbc0b2fe8b0
Source dataset
uspto-grants-1990_05
Patent number
US04921862

Reaction notes

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