HCID 23052546, compound → HCID 23052545, compound

HRID 1650805Notes

Reaction equation

HRID 1650805 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([O:8][C:9]([F:15])([F:14])[C:10]([F:13])([F:12])[F:11])[C:5]([Cl:16])=[CH:4][C:3]=1[N+:17]([O-])=O>O1CCCC1.[Ni]>[Cl:1][C:2]1[CH:7]=[C:6]([O:8][C:9]([F:14])([F:15])[C:10]([F:12])([F:13])[F:11])[C:5]([Cl:16])=[CH:4][C:3]=1[NH2:17]

Participants

4

Reactant 1

HCID 23052546HCID 23052546, compound

Product 1

HCID 23052545HCID 23052545, compound

Reagents, catalysts & solvents 2

HCID 935NickelCatalystHCID 8028TetrahydrofuranSolvent

Procedure

41 g of 2,5-dichloro-4-pentafluoroethoxynitrobenzene are dissolved in 410 ml of tetrahydrofuran and hydrogenated at room temperature for 32 hours in the presence of Raney nickel (H2 absorption: 7.62 l). The reaction mixture is filtered and concentrated and the residue is distilled. The title compound of formula ##STR13## is obtained in the form of a colourless liquid; b.p. 56°-61° C./0.04 torr.

Workup

  1. filtrationThe reaction mixture is filtered
  2. concentrationconcentrated
  3. distillationthe residue is distilled

Sources & evidence

ORD record
ord-be254f12b6e844c888b5b5aae2081f17
Source dataset
uspto-grants-1990_05
Patent number
US04925875

Reaction notes

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