HRID1650928

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccccc3)C(=O)N2[C@H]1C(=O)O

HCID6249

Ampicillin

C16H19N3O4S

结构：CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccc(O)cc3)C(=O)N2[C@H]1C(=O)O

HCID33613

Amoxicillin

C16H19N3O5S

HCID70134

Benzeneacetic acid, .alpha.-amino-, (.alpha.R)-

C8H9NO2

结构：CC(=O)OCC1=C(C(=O)O)N2C(=O)[C@@H](N)[C@H]2SC1

HCID441328

7-Aminocephalosporanic acid

C10H12N2O5S

PRODUCTS

生成物

结构：CC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)[C@H](N)C3=CCC=CC3)[C@H]2SC1

HCID38103

Cephradine

C16H19N3O4S

PROCEDURE

实验过程

As an example, D-(-)-(4-hydroxyphenyl)-glycine and D-(-)-phenylglycine are key intermediates in the industrial synthesis of amoxycillin and ampicillin respectively; while D-(-)-2-amino-2-(1,4-cylcohexadien-1-yl)acetic acid may be conveniently be employed in the acylation of 7-amino-cephalosporanic acid to give cefradin.