Triphenylphosphine → HCID 86743962, compound

HRID 1651374Notes

Reaction equation

HRID 1651374 reaction equation
[C:1]1([P:7]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Br:20][CH2:21][C:22]([O:24][CH2:25][CH2:26][O:27][CH2:28][CH2:29][O:30][CH3:31])=[O:23]>C1(C)C=CC=CC=1>[Br-:20].[CH3:31][O:30][CH2:29][CH2:28][O:27][CH2:26][CH2:25][O:24][C:22]([CH2:21][P+:7]([C:1]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1)([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1)=[O:23]

Participants

4

Reactant 2

HCID 11776TriphenylphosphineHCID 2213882-(2-methoxyethoxy)ethyl bromoacetate

Product 1

HCID 86743962HCID 86743962, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent2×

Procedure

A solution of 12.8 g (49 mmol) of triphenylphosphine in 80 ml of toluene was treated within 10 minutes with a solution of 10.7 g (44.3 mmol) of 2-(2-methoxyethoxy)ethyl bromoacetate in 20 ml of toluene. The reaction mixture was stirred at room temperature for 4 hours. The precipitate was filtered off, washed with toluene and dried in a water-jet vacuum. There was obtained [[[2-(2-methoxyethoxy)-ethoxy]carbonyl]methyl]triphenylphosphonium bromide which is processed directly.

Workup

  1. filtrationThe precipitate was filtered off
  2. washwashed with toluene
  3. dry with materialdried in a water-jet vacuum

Sources & evidence

ORD record
ord-b0ba0198cbeb487fb22403743dba36ba
Source dataset
uspto-grants-1990_05
Patent number
US04927958

Reaction notes

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