Ethyl oxoacetate → HCID 23051224, compound

HRID 1651443Notes

Reaction equation

HRID 1651443 reaction equation
[C:1]1([C:7]([NH:9][NH2:10])=[S:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:11]([O:15][CH2:16][CH3:17])(=[O:14])[CH:12]=O>C(O)C>[C:1]1([C:7]2[S:8][CH:12]([C:11]([O:15][CH2:16][CH3:17])=[O:14])[NH:10][N:9]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 2

HCID 70211Ethyl oxoacetateHCID 3361911N-aminobenzenecarbothioamide

Product 1

HCID 23051224HCID 23051224, compoundYield 112.7%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of benzenecarbothioic acid hydrazide (0.4g) and ethyl glyoxylate (0.4g) in ethanol (1 ml) was stirred at room temperature for 2 hours. The solvent was removed by evaporation and the residue re-evaporated with toluene (x2) to yield the sub-title product (0.7g) as a gum.

Workup

  1. customThe solvent was removed by evaporation
  2. customthe residue re-evaporated with toluene (x2)

Sources & evidence

ORD record
ord-bd696e77a25c4170ada5996daf50015e
Source dataset
uspto-grants-1990_05
Patent number
US04927822

Reaction notes

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