Benzyl Chloride → HCID 15611864, compound

HRID 1651471Notes

Reaction equation

HRID 1651471 reaction equation
[C:1]([O:6][CH2:7][CH2:8][N:9]([CH3:11])[CH3:10])(=[O:5])[CH2:2][CH2:3][CH3:4].[CH2:12]([Cl:19])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>C(OC(C)C)(C)C>[Cl-:19].[CH2:12]([N+:9]([CH2:8][CH2:7][O:6][C:1](=[O:5])[CH2:2][CH2:3][CH3:4])([CH3:10])[CH3:11])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

4

Reactant 2

HCID 7503Benzyl ChlorideHCID 85508Butanoic acid, 2-(dimethylamino)ethyl ester

Product 1

HCID 15611864HCID 15611864, compound

Reagents, catalysts & solvents 1

HCID 7914Diisopropyl EtherSolvent

Procedure

In 20 ml of isopropyl ether were dissolved 4.47 g (30 millimoles) of 2-dimethylaminoethyl butyrate ##STR8## and 3.8 g (30 millimoles) of benzyl chloride, and the solution was left to stand at room temperature for 4 days. The solvent was then evaporated. The crystals that precipitated were separated by suction filtration, washed fully with isopropyl ether, and dried under reduced pressure to give N-benzyl-N-(2-butyryloxyethyl)-N,N-dimethylammonium chloride (compound No. 29 in Table 1 given hereinbelow) represented by the following formula. ##STR9##

Workup

  1. waitthe solution was left
  2. customThe solvent was then evaporated
  3. customThe crystals that precipitated
  4. customwere separated by suction filtration
  5. washwashed fully with isopropyl ether
  6. customdried under reduced pressure

Sources & evidence

ORD record
ord-1d7c8240ab4442748f4da4a6d95fdee2
Source dataset
uspto-grants-1990_05
Patent number
US04929267

Reaction notes

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