Methanol → 1-(4-chlorobenzyl)nipecotic acid
Reaction equation
[CH2:23]1[O:24][CH2:25][CH2:26][CH2:27]1.[CH3:28][OH:29].[Cl:3][c:4]1[cH:5][cH:6][c:7]([CH2:8][N:9]2[CH2:10][CH:11]([C:12](=[O:13])[O:14][CH2:15][CH3:16])[CH2:17][CH2:18][CH2:19]2)[cH:20][cH:21]1.[Li+:2].[OH-:1].[OH2:22]>>[Cl:3][c:4]1[cH:5][cH:6][c:7]([CH2:8][N:9]2[CH2:10][CH:11]([C:12](=[O:13])[OH:14])[CH2:17][CH2:18][CH2:19]2)[cH:20][cH:21]1Participants
7
Sources & evidence
- ORD record
- ord-5cea0291aca24be9adab4e4959c1e086
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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