Benzoyl chloride → HCID 145809022, compound

HRID 1651538Notes

Reaction equation

HRID 1651538 reaction equation
[C:1]1([O:7][C:8](=[NH:10])[NH2:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C(N(CC)CC)C.[C:18](Cl)(=[O:25])[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1>C(Cl)(Cl)Cl>[C:18]([NH:10][C:8](=[NH:9])[O:7][C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)(=[O:25])[C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1

Participants

5

Reactant 3

HCID 7412Benzoyl chlorideHCID 8471TriethylamineHCID 22078344HCID 22078344, compound

Product 1

HCID 145809022HCID 145809022, compoundYield 73.1%

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

O-phenylisourea (1 g) was dissolved in chloroform (50 ml) and triethylamine (1.2 g) and thereafter benzoylchloride (0.8 g) were added at 0° to 5° C. After stirring for one hour at 0° to 5° C., the mixture was washed with water and the chloroform was evaporated off under reduced pressure to give N-benzoyl-O-phenylisourea (1 g), m.p. 125.1° C.

Workup

  1. washthe mixture was washed with water
  2. customthe chloroform was evaporated off under reduced pressure

Sources & evidence

ORD record
ord-d394544b974b4ba796d2b87890b8d2b3
Source dataset
uspto-grants-1990_05
Patent number
US04929628

Reaction notes

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