反应详情

A mixture of 2-(3-trifluoromethylbenzoyl)nicotinic acid (1.5 g) and hydrazine hydrate (0.4 g) in ethanol was heated at the reflux temperature for 5 hours. On cooling and reduction of the volume of solvent by evaporation, a precipitate formed which was collected by filtration, to give the title compound as a white solid, 1.08 g, m.p. 210°-215° C.

1. temperaturewas heated at the reflux temperature for 5 hours
2. temperatureOn cooling
3. customreduction of the volume of solvent by evaporation
4. customa precipitate formed which
5. filtrationwas collected by filtration