反应详情

温度

80 °C

16.5 g of ethyl [2-[(4-chlorophenyl)sulfonylaminomethyl)indan-5-yl]acetate was suspended in 50 ml of 1N sodium hydroxide, and heated at 80° C. for 1 hour. After cooling, conc. HCl was added thereto to make the system acidic. The precipitates were collected by filtration, followed by recrystallization from 80% ethanol to obtain 14.0 g of colorless needles. Yield: 91%

1. temperatureAfter cooling
2. filtrationThe precipitates were collected by filtration
3. customfollowed by recrystallization from 80% ethanol