L-Phenylalanine → HCID 15076054, compound

HRID 1655720Notes

Reaction equation

[NH2:1][C@H:2]([C:10]([OH:12])=[O:11])[CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.Cl[C:14]([O:16][CH2:17][CH:18]([CH3:20])[CH3:19])=[O:15]>>[CH2:17]([O:16][C:14]([NH:1][C@H:2]([C:10]([OH:12])=[O:11])[CH2:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)=[O:15])[CH:18]([CH3:20])[CH3:19]

Participants

Reactant 2

HCID 6140L-Phenylalanine

HCID 62365Isobutyl chloroformate

Product 1

HCID 15076054HCID 15076054, compound

Procedure

Treatment of L-phenylalanine with isobutyl chloroformate in a manner analogous to that described above, yielded yielded the desired acid as an oil [MS: 266 (M+H)+ ] which crystallized out upon standing and which was used directly in the next step.

Workup

customyielded

Sources & evidence

ORD record: ord-6d1aecac9dbb442d92784c55b94d0ed5
Source dataset: uspto-grants-1993_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05250517

Reaction notes

Loading…