Allylamine → HCID 178457519, compound

HRID 1656501Notes

Reaction equation

HRID 1656501 reaction equation
[ClH:1].[C:2](=[NH:12])(OCC)[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[CH2:13]([NH2:16])[CH:14]=[CH2:15]>CO>[ClH:1].[CH2:13]([NH:16][C:2](=[NH:12])[C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][CH:8]=1)[CH:14]=[CH2:15]

Participants

4

Reactant 2

HCID 7853AllylamineHCID 79249Benzenecarboximidic acid, ethyl ester, hydrochloride (1:1)

Product 1

HCID 178457519HCID 178457519, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a solution of ethyl benzimidate hydrochloride (20 g) in methanol at 0° C. was added allyl amine. The resulting solution was allowed to stand for 2 days at 5° C. before it was evaporated to yield a solid which was collected and washed with ether to give N-allyl benzamidine hydrochloride (21.5 g) as a white solid; 300 MHz NMR: 10.1 (s,1), 9.68 (s,1), 9.29 (s,1), 7.72 (s,5), 5.92 (m,1), 5.35 (d,2), 5.26 (d,2), 4.14 (s,2).

Workup

  1. customwas evaporated
  2. customto yield a solid which
  3. customwas collected
  4. washwashed with ether

Sources & evidence

ORD record
ord-25773a2f389f4d819f3d691f63b78d12
Source dataset
uspto-grants-1993_10
Patent number
US05254558

Reaction notes

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