2-Bromomethylnaphthalene → HCID 86733502, compound

HRID 1657458Notes

Reaction equation

HRID 1657458 reaction equation
[CH3:1][CH:2]([C:7]1[CH:8]=[C:9]([OH:25])[C:10]2[C:11]([C:19]3[CH:24]=[CH:23][N:22]=[CH:21][CH:20]=3)=[CH:12][C:13]([CH3:18])([CH3:17])[O:14][C:15]=2[CH:16]=1)[CH2:3][CH2:4][CH2:5][CH3:6].[Br:26][CH2:27][C:28]1[CH:37]=[CH:36][C:35]2[C:30](=[CH:31][CH:32]=[CH:33][CH:34]=2)[CH:29]=1>CC(C)=O>[Br-:26].[CH3:1][CH:2]([C:7]1[CH:16]=[C:15]2[C:10]([C:11]([C:19]3[CH:24]=[CH:23][N+:22]([CH2:27][C:28]4[CH:37]=[CH:36][C:35]5[C:30](=[CH:31][CH:32]=[CH:33][CH:34]=5)[CH:29]=4)=[CH:21][CH:20]=3)=[CH:12][C:13]([CH3:18])([CH3:17])[O:14]2)=[C:9]([OH:25])[CH:8]=1)[CH2:3][CH2:4][CH2:5][CH3:6]

Participants

4

Reactant 2

HCID 703202-BromomethylnaphthaleneHCID 54199631HCID 54199631, compound

Product 1

HCID 86733502HCID 86733502, compoundYield 99.1%

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

7-(2-Hexyl)-2,2-dimethyl-4-(4-pyridyl)-2H-chromen-5-ol (5.00 g), 2-bromomethyl-naphthalene (3.54 g) and acetone (70 ml) were heated together under reflux for 6 hours. The resulting pale yellow precipitate was filtered and dried to yield 4-[7-(2-hexyl)-5-hydroxy-2,2-dimethyl-2H-chromen-4-yl]-1-(2-naphthylmethyl) pyridinium bromide (8.20 g) m.p. 236°- 239°.

Workup

  1. temperatureunder reflux for 6 hours
  2. filtrationThe resulting pale yellow precipitate was filtered
  3. customdried

Sources & evidence

ORD record
ord-e49c9d11042e49dcaa7ffb439fa2d2b7
Source dataset
uspto-grants-1976_06
Patent number
US03960879

Reaction notes

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