Sodium Bicarbonate → sodium 7-methoxy-1-oxo-1H-2-benzothiopyran-3-carboxylate

HRID 1657477Notes

Reaction equation

HRID 1657477 reaction equation
[CH3:1][O:2][C:3]1[CH:16]=[CH:15][C:6]2[CH:7]=[C:8]([C:12]([OH:14])=[O:13])[S:9][C:10](=[O:11])[C:5]=2[CH:4]=1.C(=O)(O)[O-].[Na+:21]>O>[CH3:1][O:2][C:3]1[CH:16]=[CH:15][C:6]2[CH:7]=[C:8]([C:12]([O-:14])=[O:13])[S:9][C:10](=[O:11])[C:5]=2[CH:4]=1.[Na+:21]

Participants

4

Reactant 2

HCID 516892Sodium BicarbonateHCID 214407427-methoxy-1-oxo-1H-2-benzothiopyran-3-carboxylic acid

Product 1

HCID 23666647sodium 7-methoxy-1-oxo-1H-2-benzothiopyran-3-carboxylate

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To a stirred suspension of 2.0347 g. (8.613 mM) of 7-methoxy-1-oxo-1H-2-benzothiopyran-3-carboxylic acid in 50 ml. of distilled water is added 0.7236 g. (8.613 mM) of sodium bicarbonate. The resulting mixture is stirred at 25°-35° for 1.25 hours, filtered, and the filtrate freeze-dried to give sodium 7-methoxy-1-oxo-1H-2-benzothiopyran-3-carboxylate as a pale yellow solid, m.p. >350°.

Workup

  1. additionTo a stirred suspension of 2.0347 g
  2. filtrationfiltered
  3. customthe filtrate freeze-dried

Sources & evidence

ORD record
ord-a29111a5346149898d556cf6a9571d0b
Source dataset
uspto-grants-1976_06
Patent number
US03960892

Reaction notes

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