Sodium Bicarbonate → sodium 4-methyl-1-oxo-1H-2-benzothiopyran-3-carboxylate

HRID 1657483Notes

Reaction equation

HRID 1657483 reaction equation
[CH3:1][C:2]1[C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=2[C:5](=[O:12])[S:4][C:3]=1[C:13]([OH:15])=[O:14].C(=O)(O)[O-].[Na+:20]>O>[CH3:1][C:2]1[C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][C:6]=2[C:5](=[O:12])[S:4][C:3]=1[C:13]([O-:15])=[O:14].[Na+:20]

Participants

4

Reactant 2

HCID 516892Sodium BicarbonateHCID 214236814-methyl-1-oxo-1H-2-benzothiopyran-3-carboxylic acid

Product 1

HCID 23666645sodium 4-methyl-1-oxo-1H-2-benzothiopyran-3-carboxylate

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

To a stirred suspension of 2.0090 g. (9.122 mM) of 4-methyl-1-oxo-1H-2-benzothiopyran-3-carboxylic acid in 50 ml. of distilled water is added 0.7663 g. (9.122 mM) of sodium bicarbonate. After stirring at room temperature for 1.5 hours, the solution is filtered and the filtrate freeze-dried to give sodium 4-methyl-1-oxo-1H-2-benzothiopyran-3-carboxylate, m.p. 330° (dec.).

Workup

  1. additionTo a stirred suspension of 2.0090 g
  2. filtrationthe solution is filtered
  3. customthe filtrate freeze-dried

Sources & evidence

ORD record
ord-9b6f3ee43167472f945a7f437988a238
Source dataset
uspto-grants-1976_06
Patent number
US03960892

Reaction notes

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