HCID 21534860, compound → HCID 21534824, compound

HRID 1657595Notes

Reaction equation

HRID 1657595 reaction equation
[CH3:1][O:2][C:3]1[CH:16]=[CH:15][C:14]2[S:13][C:12]3[C:7]([C:8](=O)[CH:9]=[CH:10][C:11]=3[S:17]([CH3:20])(=[O:19])=[O:18])=[N:6][C:5]=2[CH:4]=1>CN(C)C=O.C(O)(=O)C.[Zn]>[CH3:1][O:2][C:3]1[CH:16]=[CH:15][C:14]2[S:13][C:12]3[C:7](=[CH:8][CH:9]=[CH:10][C:11]=3[S:17]([CH3:20])(=[O:19])=[O:18])[NH:6][C:5]=2[CH:4]=1

Participants

5

Reactant 1

HCID 21534860HCID 21534860, compound

Product 1

HCID 21534824HCID 21534824, compoundYield 35.7%

Reagents, catalysts & solvents 3

HCID 23994ZincCatalystHCID 176Acetic AcidSolventHCID 6228DimethylformamideSolvent

Procedure

2-Methoxy-6-methylsulphonylphenothiazine (m.p. 204°-206°C.; 16.05 g.) is prepared by reduction of 2-methoxy-6-methylsulphonyl-9-oxophenothiazine (47 g.) by means of zinc powder (28 g.) in dimethylformamide (175 cc.), acetic acid (73 cc.) and distilled water (73 cc.).

Workup

  1. distillationdistilled water (73 cc.)

Sources & evidence

ORD record
ord-5465a5b2b11e4021abc8dc1dcadc7889
Source dataset
uspto-grants-1976_06
Patent number
US03961055

Reaction notes

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