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HRID1657605

反应详情

EQUATION

反应方程式

HRID 1657605 的结构方程式

REACTANTS

反应物

3
结构：ClCCCBr
HCID8006

1-Bromo-3-chloropropane

C3H6BrCl

结构：[K+].[OH-]
HCID14797

Potassium hydroxide

HKO

结构：CN(C)S(=O)(=O)c1cccc2c1Sc1ccc(OCc3ccccc3)cc1N2
HCID21534823

未命名化合物

PRODUCTS

生成物

1
结构：CN(C)S(=O)(=O)c1cccc2c1Sc1ccc(OCc3ccccc3)cc1N2CCCCl
HCID21534843

未命名化合物

收率 108.8%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCC(C)=O
溶剂HCID6569

Methyl ethyl ketone

C4H8O

PROCEDURE

实验过程

2-Benzyloxy-6-dimethylsulphamoyl-10-(3-chloro-propyl)phenothiazine (m.p. 124°-126°C.; 89.0 g.) is prepared by reacting 1-bromo-3-chloropropane (92 g.) with 2-benzyloxy-6-dimethylsulphamoylphenothiazine (69.0 g.) in the presence of powdered potassium hydroxide (16.4 g.) in methyl ethyl ketone (230 cc.).