Hydrochloric Acid → 4-Chloro-2-[4-(3-chloropyridin-2-yl)piperazin-1-yl]-6-trifluoromethyl-1H-benzoimidazole

HRID 165785Notes

Reaction equation

HRID 165785 reaction equation
[CH:30]([N:31]([CH2:32][CH3:33])[CH:34]([CH3:35])[CH3:36])([CH3:37])[CH3:38].[Cl:15][c:16]1[n:17][c:18]2[c:19]([nH:20]1)[cH:21][c:22]([C:26]([F:27])([F:28])[F:29])[cH:23][c:24]2[Cl:25].[Cl:2][c:3]1[c:4]([N:9]2[CH2:10][CH2:11][NH:12][CH2:13][CH2:14]2)[n:5][cH:6][cH:7][cH:8]1.[ClH:1]>>[Cl:2][c:3]1[c:4]([N:9]2[CH2:10][CH2:11][N:12]([c:16]3[n:17][c:18]4[c:19]([nH:20]3)[cH:21][c:22]([C:26]([F:27])([F:28])[F:29])[cH:23][c:24]4[Cl:25])[CH2:13][CH2:14]2)[n:5][cH:6][cH:7][cH:8]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 81531DiisopropylethylamineHCID 114129441-(3-Chloropyridin-2-yl)piperazineHCID 669373361H-Benzimidazole, 2,7-dichloro-5-(trifluoromethyl)-

Product 1

HCID 578351924-Chloro-2-[4-(3-chloropyridin-2-yl)piperazin-1-yl]-6-trifluoromethyl-1H-benzoimidazole

Sources & evidence

ORD record
ord-0e92e0ce889b4d959ba2fa79a4e6bc76
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…