Hydrochloric Acid → HCID 21530705, compound

HRID 1657868Notes

Reaction equation

HRID 1657868 reaction equation
[N:1]([CH2:4][CH2:5][N:6]1[CH:10]=[CH:9][N:8]=[C:7]1[CH3:11])=[N+:2]=[N-:3].[ClH:12].CCOCC>CC(O)C>[ClH:12].[N:1]([CH2:4][CH2:5][N:6]1[CH:10]=[CH:9][N:8]=[C:7]1[CH3:11])=[N+:2]=[N-:3]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 3283Diethyl EtherHCID 21530706HCID 21530706, compound

Product 1

HCID 21530705HCID 21530705, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent2×

Procedure

To a solution of 4 parts of 1-(2-azidoethyl)-2-methylimidazole in approximately 40 parts of 2-propanol is added 10 parts of a 20% solution of hydrogen chloride in 2-propanol. The precipitate which results (formation of which can be speeded by introducing a small amount of anhydrous ether) is isolated by filtration, washed with anhydrous ether, dried in air, and recrystallized from a mixture of 2-propanol and anhydrous ether to give 1-(2-azidoethyl)-2-methylimidazole hydrochloride melting at 132°-133.5°.

Workup

  1. customThe precipitate which results (formation of which
  2. customis isolated by filtration
  3. washwashed with anhydrous ether
  4. customdried in air
  5. customrecrystallized from a mixture of 2-propanol and anhydrous ether

Sources & evidence

ORD record
ord-ae67ef1f52754f7182bcbbcc88142c4d
Source dataset
uspto-grants-1976_06
Patent number
US03962274

Reaction notes

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