Hydrochloric Acid → HCID 21530696, compound

HRID 1657869Notes

Reaction equation

HRID 1657869 reaction equation
[N:1]([CH2:4][CH2:5][N:6]1[C:10]([N+:11]([O-:13])=[O:12])=[CH:9][N:8]=[CH:7]1)=[N+:2]=[N-:3].[ClH:14]>CC(O)C>[ClH:14].[N:1]([CH2:4][CH2:5][N:6]1[C:10]([N+:11]([O-:13])=[O:12])=[CH:9][N:8]=[CH:7]1)=[N+:2]=[N-:3]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 21530697HCID 21530697, compound

Product 1

HCID 21530696HCID 21530696, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent2×

Procedure

To a solution of 6 parts of 1-(2-azidoethyl)-5-nitroimidazole in 20 parts of 2-propanol is added 7 parts of a .20% solution of hydrogen chloride in 2-propanol. The resultant precipitate is recrystallized from a mixture of 2-propanol and methanol to give 1-(2-azidoethyl)-5-nitroimidazole hydrochloride which, washed with 2-propanol and dried in air, sinters at 155° and melts in the range 167°-173° with decomposition.

Workup

  1. customThe resultant precipitate is recrystallized from a mixture of 2-propanol and methanol

Sources & evidence

ORD record
ord-817ab0de9d90411f815490663ff20af9
Source dataset
uspto-grants-1976_06
Patent number
US03962274

Reaction notes

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