Dimethylformamide → 2,6-Diethylacetanilide

HRID 1657928Notes

Reaction equation

HRID 1657928 reaction equation
[CH2:1]([C:3]1[CH:9]=[CH:8][CH:7]=[C:6]([CH2:10][CH3:11])[C:4]=1[NH2:5])[CH3:2].CN(C)C=O.[C:17](OC(=O)C)(=[O:19])[CH3:18]>O>[CH3:2][CH2:1][C:3]1[CH:9]=[CH:8][CH:7]=[C:6]([CH2:10][CH3:11])[C:4]=1[NH:5][C:17]([CH3:18])=[O:19]

Participants

5

Reactant 3

HCID 6228DimethylformamideHCID 7918Acetic AnhydrideHCID 113692,6-Diethylaniline

Product 1

HCID 855342,6-Diethylacetanilide

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A solution of 74.5 parts of 2,6-diethylaniline in 200 parts of dimethylformamide is treated with 56 parts of acetic anhydride at 10°C. The mixture is stirred at 40° for one hour, poured into ice and water and stirred. The solid 2,6-diethylacetanilide is filtered, washed with water and dried.

Workup

  1. stirringstirred
  2. filtrationThe solid 2,6-diethylacetanilide is filtered
  3. washwashed with water
  4. customdried

Sources & evidence

ORD record
ord-00ce2b2afdf94aa8a020ec5a02a788b0
Source dataset
uspto-grants-1976_06
Patent number
US03962307

Reaction notes

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