Methane → HCID 21529934, compound

HRID 1658013Notes

Reaction equation

HRID 1658013 reaction equation
[ClH:1].C([NH:9][CH2:10][P:11](=[O:22])([O:17][CH2:18][CH2:19][CH2:20][CH3:21])[O:12][CH2:13][CH2:14][CH2:15][CH3:16])C1C=CC=CC=1.C>C(O)C.[Pd]>[ClH:1].[NH2:9][CH2:10][P:11](=[O:22])([O:12][CH2:13][CH2:14][CH2:15][CH3:16])[O:17][CH2:18][CH2:19][CH2:20][CH3:21]

Participants

5

Reactant 2

HCID 297MethaneHCID 21529918HCID 21529918, compound

Product 1

HCID 21529934HCID 21529934, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A mixture of dibutyl N-benzyl-aminomethylphosphonate hydrochloride (122.4 g) and 10% palladium on powdered charcoal (5.0 g) in ethanol (1000 ml) is hydrogenated at 40 psi for 2 hours. The catalyst is removed by filtration and the filtrate is evaporated under reduced pressure to yield dibutyl aminomethylphosphonate hydrochloride.

Workup

  1. customThe catalyst is removed by filtration
  2. customthe filtrate is evaporated under reduced pressure

Sources & evidence

ORD record
ord-6b82dbcb97b2459087c7aa630d5e5ae7
Source dataset
uspto-grants-1976_06
Patent number
US03962224

Reaction notes

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