Potassium Carbonate → HCID 54254034, compound

HRID 1658025Notes

Reaction equation

HRID 1658025 reaction equation
[CH:1]([NH:3][CH:4]([P:18]([O:27][C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1)([O:20][C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)=[O:19])[C:5]([O:7][CH2:8][C:9]1[CH:14]=[CH:13][C:12]([N+:15]([O-:17])=[O:16])=[CH:11][CH:10]=1)=[O:6])=[S:2].C(=O)([O-])[O-].[K+].[K+].Cl[CH2:41][C:42](=[O:46])[CH2:43][O:44][CH3:45]>CC(C)=O>[N+:15]([C:12]1[CH:11]=[CH:10][C:9]([CH2:8][O:7][C:5]([CH:4]([P:18]([O:20][C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)([O:27][C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)=[O:19])[N:3]=[CH:1][S:2][CH2:41][C:42](=[O:46])[CH2:43][O:44][CH3:45])=[O:6])=[CH:14][CH:13]=1)([O-:17])=[O:16]

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 203930501-chloro-3-methoxypropan-2-oneHCID 86733537HCID 86733537, compound

Product 1

HCID 54254034HCID 54254034, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A mixture of p-nitrobenzyl α-thioformamidodiphenylphosphonoacetate (2.43 g), powdered potassium carbonate (0.73 ), 1-chloro-3-methoxy-2-propanone (0.63 g), and acetone (25 ml) is stirred in a capped flask at room temperature for 16 hours. The mixture is filtered and the filtrate is evaporated in vacuo to afford 3-methoxy-2-oxopropyl N-(p-nitrobenzyloxycarbonyl-diphenylphosphonomethyl)thioformimidate.

Workup

  1. filtrationThe mixture is filtered
  2. customthe filtrate is evaporated in vacuo

Sources & evidence

ORD record
ord-d7fa3866c2584946807ddbdbbf231bb2
Source dataset
uspto-grants-1976_06
Patent number
US03962224

Reaction notes

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