Allylamine → HCID 21527620, compound

HRID 1658483Notes

Reaction equation

HRID 1658483 reaction equation
[O:1]1[CH2:15][CH:2]1[CH2:3][O:4][C:5]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:6]=1[CH2:7][C:8](=[O:14])[NH:9]2.[CH2:16]([NH2:19])[CH:17]=[CH2:18]>O1CCOCC1>[CH2:16]([NH:19][CH2:15][CH:2]([OH:1])[CH2:3][O:4][C:5]1[CH:13]=[CH:12][CH:11]=[C:10]2[C:6]=1[CH2:7][C:8](=[O:14])[NH:9]2)[CH:17]=[CH2:18]

Participants

4

Reactant 2

HCID 7853AllylamineHCID 13066242HCID 13066242, compound

Product 1

HCID 21527620HCID 21527620, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

3 g of 4-(2,3-epoxypropoxy)oxindole, 30 cc of allylamine and 70 cc of dioxane are heated to the boil for 16 hours. The mixture is evaporated to dryness at reduced pressure and the crude title compound is recrystallized from ethanol/ethyl acetate. M.P. 124°-127° .

Workup

  1. customThe mixture is evaporated to dryness at reduced pressure
  2. customthe crude title compound is recrystallized from ethanol/ethyl acetate

Sources & evidence

ORD record
ord-80e0a3b6fc68471a92f68b6237f5d798
Source dataset
uspto-grants-1976_06
Patent number
US03965095

Reaction notes

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