Hydrochloric Acid → HCID 68131268, compound

HRID 1658518Notes

Reaction equation

HRID 1658518 reaction equation
[CH3:1][N:2]1[CH2:7][CH:6]=[C:5]([CH:8]=[CH:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[CH2:4][CH2:3]1.C(O)(C)C.[ClH:20]>CCOCC>[ClH:20].[CH3:1][N:2]1[CH2:3][CH:4]=[C:5]([CH:8]=[CH:9][C:10]2[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=2)[CH2:6][CH2:7]1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 3776IsopropanolHCID 125421HCID 125421, compound

Product 1

HCID 68131268HCID 68131268, compoundYield 68%

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

To a cooled and stirred solution of 1,2,3,6-tetrahydro-1-methyl-4-styrylpyridine (53.6 g) prepared according to the method of Gautier (Ph. D. Thesis, University of New Hampshire, 1966 p. 134) in dry ether (300 ml.), isopropanol saturated with dry hydrochloric acid is added until precipitation was complete. The product after ether washing and recrystallization from methanol-ether is obtained in a 68 percent yield, which melts with decomposition at 289.5°-290°C.

Workup

  1. temperatureTo a cooled
  2. customprepared
  3. customThe product after ether washing and recrystallization from methanol-ether
  4. customis obtained in a 68 percent yield, which
  5. custommelts with decomposition at 289.5°-290°C.

Sources & evidence

ORD record
ord-a80ca6e5541d4a9d841e73fb8a4e23f4
Source dataset
uspto-grants-1976_06
Patent number
US03965102

Reaction notes

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