Methylamine → HCID 70636802, compound

HRID 1658718Notes

Reaction equation

HRID 1658718 reaction equation
O=[C:2]1[CH2:20][CH2:19][N:5]2[C:6]3[CH:18]=[CH:17][CH:16]=[CH:15][C:7]=3[CH2:8][C:9]3[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=3[CH:4]2[CH2:3]1.[CH3:21][NH2:22].[H][H]>C(O)C.[Pd]>[CH3:21][NH:22][CH:2]1[CH2:20][CH2:19][N:5]2[C:6]3[CH:18]=[CH:17][CH:16]=[CH:15][C:7]=3[CH2:8][C:9]3[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=3[CH:4]2[CH2:3]1

Participants

6

Reactant 3

HCID 6329MethylamineHCID 70637887HCID 70637887, compoundHCID 178418361HCID 178418361, compound2×

Product 1

HCID 70636802HCID 70636802, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

1 g of 2-keto-1,2,3,4,10,14b-hexahydro-pyridino[1,2-a]-dibenzo[c,f]-azepine is dissolved in 100 ml of ethanol, after which 10 ml of methylamine and 200 mg of palladium (10%) on charcoal are added. Then hydrogen is passed through this mixture until no hydrogen is absorbed any longer.

Workup

  1. customis absorbed any longer

Sources & evidence

ORD record
ord-640268115d3a4cf9b77a168aedc6fda3
Source dataset
uspto-grants-1976_06
Patent number
US03966723

Reaction notes

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