反应详情

To a solution of 1.0 g of 3-isopropyl-2-oximino-4-thiazolidinone in 50 ml acetone-acetonitrile solution (1:1) was added 1 ml of methylisocyanate and 5 drops of triethylamine. The reaction mixture was placed in a pressure bottle and left overnight at ambient temperature. After concentrating under vacuo the residual oil was diluted with diethylether. On cooling the product crystallized. Recrystallized from ethyl ether. Weight 1.8 g. m.p. 94°-96°C.

1. concentrationAfter concentrating under vacuo the residual oil
2. additionwas diluted with diethylether
3. temperatureOn cooling the product
4. customcrystallized
5. customRecrystallized from ethyl ether