Water → HCID 21516782, compound

HRID 1659177Notes

Reaction equation

HRID 1659177 reaction equation
[CH2:1]([CH:3]1[C:11](=[O:12])[C:10]2[C:5](=[CH:6][C:7]([O:15][CH3:16])=[C:8]([Cl:14])[C:9]=2[Cl:13])[C:4]1=[O:17])[CH3:2].[C:18](=O)([O-])[O-].[K+].[K+].CI.O>CN(C)C=O>[CH2:1]([C:3]1([CH3:18])[C:11](=[O:12])[C:10]2[C:5](=[CH:6][C:7]([O:15][CH3:16])=[C:8]([Cl:14])[C:9]=2[Cl:13])[C:4]1=[O:17])[CH3:2]

Participants

6

Reactant 4

HCID 962WaterHCID 6328Methyl iodideHCID 11430Potassium CarbonateHCID 21516783HCID 21516783, compound

Product 1

HCID 21516782HCID 21516782, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

A stirred solution of 2-ethyl-4,5-dichloro-6-methoxyindan-1,3-dione (1.3 g.) in dimethylformamide (15 ml.) is treated with potassium carbonate (1.26 g.) and metyl iodide. After 15 minutes, the reaction is poured into water (75 ml.) affording 1.3 g. of 2-ethyl-2-methyl-4,5-dichloro-6-methoxyindan-1,3-dione which melts at 157°C. after recrystallization from ethanol.

Workup

  1. customaffording 1.3 g
  2. customof 2-ethyl-2-methyl-4,5-dichloro-6-methoxyindan-1,3-dione which melts at 157°C. after recrystallization from ethanol

Sources & evidence

ORD record
ord-e169ab2fb667430abc861c7f4d125a81
Source dataset
uspto-grants-1976_06
Patent number
US03966966

Reaction notes

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