Dimethylformamide → 1-ethyl-3-[4-[4-(3-methylmorpholin-4-yl)-7-(pyrazine-2-carbonyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea
Reaction equation
[CH2:1]([CH3:2])[NH:3][C:4](=[O:5])[NH:6][c:7]1[cH:8][cH:9][c:10](-[c:13]2[n:14][c:15]([N:23]3[CH:24]([CH3:29])[CH2:25][O:26][CH2:27][CH2:28]3)[c:16]3[c:17]([n:18]2)[CH2:19][NH:20][CH2:21][CH2:22]3)[cH:11][cH:12]1.[CH3:30][N:31]([CH3:32])[CH:33]=[O:34].[CH:35]([N:36]([CH2:37][CH3:38])[CH:39]([CH3:40])[CH3:41])([CH3:42])[CH3:43].[n:44]1[c:45]([C:50](=[O:51])[Cl:52])[cH:46][n:47][cH:48][cH:49]1>>[CH2:1]([CH3:2])[NH:3][C:4](=[O:5])[NH:6][c:7]1[cH:8][cH:9][c:10](-[c:13]2[n:14][c:15]([N:23]3[CH:24]([CH3:29])[CH2:25][O:26][CH2:27][CH2:28]3)[c:16]3[c:17]([n:18]2)[CH2:19][N:20]([C:50]([c:45]2[n:44][cH:49][cH:48][n:47][cH:46]2)=[O:51])[CH2:21][CH2:22]3)[cH:11][cH:12]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-843e3f210b2541c0b3fd0645ffc5b48e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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