Diethyl Ether → 1-(3-(6,7-Dimethoxyquinazolin-4-ylthio)phenyl)-3-(5-(1,1,1-trifluoro-2-methylpropan-2-yl)isoxazol-3-yl)urea
Reaction equation
[CH2:51]1[O:52][CH2:53][CH2:54][CH2:55]1.[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6]([S:15][c:16]3[cH:17][c:18]([NH2:19])[cH:20][cH:21][cH:22]3)[n:7][cH:8][n:9][c:10]2[cH:11][c:12]1[O:13][CH3:14].[CH3:46][CH2:47][O:48][CH2:49][CH3:50].[CH3:56][N:57]([CH3:58])[c:59]1[cH:60][cH:61][n:62][cH:63][cH:64]1.[F:23][C:24]([C:25]([CH3:26])([CH3:27])[c:28]1[cH:29][c:30]([NH:33][C:34]([O:35][c:37]2[cH:38][cH:39][c:40]([Cl:41])[cH:42][cH:43]2)=[O:36])[n:31][o:32]1)([F:44])[F:45]>>[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6]([S:15][c:16]3[cH:17][c:18]([NH:19][C:34]([NH:33][c:30]4[cH:29][c:28]([C:25]([C:24]([F:23])([F:44])[F:45])([CH3:26])[CH3:27])[o:32][n:31]4)=[O:35])[cH:20][cH:21][cH:22]3)[n:7][cH:8][n:9][c:10]2[cH:11][c:12]1[O:13][CH3:14]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-cbf8d8c03d624de59193f5aa06fe9ec9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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