HRID1659899

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID7237

o-Xylene

C8H10

HCID27902

N-(2-Hydroxyethyl)octadecanamide

C20H41NO2

结构：CC(C)(C)c1cc(CCC(=O)O)cc(C(C)(C)C)c1O

HCID88389

Fenozan

C17H26O3

PRODUCTS

生成物

结构：CCCCCCCCCCCCCCCCCC(=O)NCCOC(=O)CCc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

HCID20558491

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

结构：CCCC[O-].CCCC[O-].CCCC[O-].CCCC[O-].[Ti+4]

催化剂HCID21801

Titanium(IV) n-butoxide

C16H36O4Ti

溶剂HCID962

Water

H2O

PROCEDURE

实验过程

A mixture of 30.6 g (0.11 mole) 3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionic acid, 32.6 g (0.1 mole) N-(2-hydroxyethyl)stearamide, 0.8 g Tyzor TBT, and 100 ml xylene was refluxed for six hours. The water (1.8 ml) was trapped in a Stark & Dean trap. The solution was filtered through Microcel (trademark, synthetic calcium silicate) and the solvent was removed by vacuum stripping. The title compound (51 g) was recrystallized from acrylonitrile. It melted at 52°-55° C.

WORKUP

后处理

temperaturewas refluxed for six hours
filtrationThe solution was filtered through Microcel (trademark, synthetic calcium silicate)
customthe solvent was removed by vacuum stripping
customThe title compound (51 g) was recrystallized from acrylonitrile

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-17febe92b6be438884d353ab4e1d39ed
来源数据集: uspto-grants-1981_12
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04305868
来源说明: uspto-grants-1981_12

反应 SMILES

[C:1]([C:5]1[CH:6]=[C:7]([CH2:16][CH2:17][C:18]([OH:20])=[O:19])[CH:8]=[C:9]([C:12]([CH3:15])([CH3:14])[CH3:13])[C:10]=1[OH:11])([CH3:4])([CH3:3])[CH3:2].O[CH2:22][CH2:23][NH:24][C:25](=[O:43])[CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH3:42].C1(C)C(C)=CC=CC=1>CCCC[O-].CCCC[O-].CCCC[O-].CCCC[O-].[Ti+4].O>[C:1]([C:5]1[CH:6]=[C:7]([CH2:16][CH2:17][C:18]([O:20][CH2:22][CH2:23][NH:24][C:25](=[O:43])[CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH3:42])=[O:19])[CH:8]=[C:9]([C:12]([CH3:13])([CH3:14])[CH3:15])[C:10]=1[OH:11])([CH3:4])([CH3:2])[CH3:3]