Hydrochloric Acid → HCID 11393961, compound

HRID 1659901Notes

Reaction equation

HRID 1659901 reaction equation
[C:1]([C:5]1[CH:6]=[C:7]([CH2:16][CH2:17][C:18]2[O:19][CH2:20][C:21]([CH3:24])([CH3:23])[N:22]=2)[CH:8]=[C:9]([C:12]([CH3:15])([CH3:14])[CH3:13])[C:10]=1[OH:11])([CH3:4])([CH3:3])[CH3:2].C([OH:28])(C)C.Cl.[OH-].[Na+]>O>[C:1]([C:5]1[CH:6]=[C:7]([CH2:16][CH2:17][C:18]([O:19][CH2:20][C:21]([NH2:22])([CH3:24])[CH3:23])=[O:28])[CH:8]=[C:9]([C:12]([CH3:15])([CH3:14])[CH3:13])[C:10]=1[OH:11])([CH3:2])([CH3:3])[CH3:4]

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 3776IsopropanolHCID 14798Sodium HydroxideHCID 20558486HCID 20558486, compound

Product 1

HCID 11393961HCID 11393961, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
45 °C

Procedure

In a 1-liter, three-neck, round-bottom flask equipped with a thermometer, stirrer and condenser were placed 66.2 g (0.2 mole) 2-[2-(3,5-di-tert-butyl-4-hydroxyphenyl)ethyl]-4,4-dimethyl-2-oxazoline, prepared as disclosed in inventors' application Ser. No. 043,787, filed on May 30, 1979, now abandoned and application Ser. No. 181,325, filed on Aug. 25, 1980 which is a continuation of said application Ser. No. 043,787, entitled "Derivatives of 2-Oxazolines as antioxidants," assigned to Uniroyal, Inc. and filed concurrently herewith, the disclosure of which is hereby incorporated herein by reference, 400 ml isopropanol and 33 ml 6 N hydrochloric acid. The mixture was heated to 45° C. for 2 hours and then cooled. To this stirred solution were added 250 ml of water and 33 ml of 6 N sodium hydroxide. The product was removed by filtration and dried. The title compound, (52 g), thus obtained, melted at 97°-99° C.

Workup

  1. customIn a 1-liter, three-neck, round-bottom flask equipped with a thermometer, stirrer and condenser
  2. customprepared
  3. temperaturecooled
  4. customThe product was removed by filtration
  5. customdried

Sources & evidence

ORD record
ord-b854f07685744a6abecd37c64d832330
Source dataset
uspto-grants-1981_12
Patent number
US04305868

Reaction notes

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