Butyl Chloride → HCID 20506490, compound

HRID 1659959Notes

Reaction equation

HRID 1659959 reaction equation
[OH:1][CH:2]1[CH2:7][CH2:6][CH2:5][N:4]([C:8]2[C:17]3[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=3)[N:11]=[C:10]([C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)[N:9]=2)[CH2:3]1.[CH2:24](Cl)[CH2:25][CH2:26][CH3:27]>CN(C)C=O>[CH2:24]([O:1][CH:2]1[CH2:7][CH2:6][CH2:5][N:4]([C:8]2[C:17]3[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=3)[N:11]=[C:10]([C:18]3[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=3)[N:9]=2)[CH2:3]1)[CH2:25][CH2:26][CH3:27]

Participants

4

Reactant 2

HCID 8005Butyl ChlorideHCID 24407555HCID 24407555, compound

Product 1

HCID 20506490HCID 20506490, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Equimolar amounts of 4-(3-hydroxypiperidinyl-2-phenylquinazoline and soda amide are mixed in dimethylformamide and reacted with butyl chloride to prepare the title compound.

Sources & evidence

ORD record
ord-ade5abaac5ef4dc0ad4a35d6f145ddbf
Source dataset
uspto-grants-1981_12
Patent number
US04306065

Reaction notes

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