Hydrochloric Acid → HCID 178526838, compound

HRID 1661038Notes

Reaction equation

HRID 1661038 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[CH:4][N:3]=1.Cl.[Cl:12]([O-])(=O)=O.[Na+]>O>[OH:1][C:2]1[C:7]([Cl:12])=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[CH:4][N:3]=1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 516902Sodium ChlorateHCID 178526703HCID 178526703, compound

Product 1

HCID 178526838HCID 178526838, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
50 °C

Procedure

2-Hydroxy-5-nitro pyridine (1 g, 7.14 mmol) was added portion wise to 4.5 mL of concentrated HCl under constant stirring and then heated to 50° C. To this was slowly added a solution of sodium chlorate (266 mg, 2.5 mmol) in water (4 mL). The reaction was maintained at the same temperature for an additional hour, and then cooled to 0° C. The precipitate obtained was filtered, washed thoroughly with water and dried to obtain 2-hydroxy-3-chloro-5-nitro pyridine.

Workup

  1. temperatureThe reaction was maintained at the same temperature for an additional hour
  2. temperaturecooled to 0° C
  3. customThe precipitate obtained
  4. filtrationwas filtered
  5. washwashed thoroughly with water
  6. customdried

Sources & evidence

ORD record
ord-ea6de33fafff4984843ef9cda639ec04
Source dataset
uspto-grants-2011_10
Patent number
US08030324B2

Reaction notes

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