反应详情

温度

80 °C

3.51 g of 4-picoline and 5 g of disulfanediyldiethane-2,1-diyl dimethanesulfonate are diluted in 5 mL of N-methylpyrrolidinone (NMP) and then heated at 80° C. with stirring for 2 hours. Stirring is continued at room temperature for 17 hours. The reaction medium is made up with 50 mL of ethyl acetate and then filtered, washed with three times 100 mL of EtOAC and dried under vacuum over P2O5. 7.29 g of brown powder are collected. The analyses indicate that the product is in accordance and pure.

1. stirringStirring
2. waitis continued at room temperature for 17 hours
3. filtrationfiltered
4. washwashed with three times 100 mL of EtOAC
5. dry with materialdried under vacuum over P2O5
6. custom7.29 g of brown powder are collected