Trifluoroacetic acid → HCID 58036020, compound

HRID 1663281Notes

Reaction equation

HRID 1663281 reaction equation
[CH:1]1[C:13]2[CH2:12][C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[C:5]=2[CH:4]=[CH:3][C:2]=1[CH:14]=O.[NH2:16][C:17]1[CH:29]=[CH:28][C:27]2[C:26]3[C:21](=[CH:22][C:23]([NH2:30])=[CH:24][CH:25]=3)[CH2:20][C:19]=2[CH:18]=1.C(O)(C(F)(F)F)=O>C(O)(C)C>[CH:1]1[C:13]2[CH2:12][C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[C:5]=2[CH:4]=[CH:3][C:2]=1[CH:14]=[N:16][C:17]1[CH:29]=[CH:28][C:27]2[C:26]3[C:21](=[CH:22][C:23]([NH2:30])=[CH:24][CH:25]=3)[CH2:20][C:19]=2[CH:18]=1

Participants

5

Reactant 3

HCID 6422Trifluoroacetic acidHCID 106792,7-DiaminofluoreneHCID 34804Fluorene-2-carboxaldehyde

Product 1

HCID 58036020HCID 58036020, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

2-Fluorenecarboxaldehyde (49.5 mg, 0.25 mmol) was added to 2,7-diaminofluorene (50 mg, 0.25 mmol) in anhydrous isopropanol, under an N2 atmosphere and a catalytic amount of TFA. No heating was required. The reaction was run for 12 hours until a green precipitate was filtered, yielding 94.9 mg. of the title compound.

Workup

  1. filtrationwas filtered
  2. customyielding 94.9 mg

Sources & evidence

ORD record
ord-2c37f24e6e424cb6b29ce847fd7b63cd
Source dataset
uspto-grants-2011_10
Patent number
US08034895B2

Reaction notes

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