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HRID1665039

反应详情

EQUATION

反应方程式

HRID 1665039 的结构方程式

REACTANTS

反应物

3
结构：CCN(C(C)C)C(C)C
HCID81531

Diisopropylethylamine

C8H19N

结构：O=S(=O)(Cl)c1cccc(Cl)c1F
HCID2778321

3-Chloro-2-fluorobenzenesulfonyl chloride

C6H3Cl2FO2S

结构：CC(C)CNCc1ccc(-c2cccc(S(C)(=O)=O)c2)s1
HCID67441398

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)CN(Cc1ccc(-c2cccc(S(C)(=O)=O)c2)s1)S(=O)(=O)c1cccc(Cl)c1F
HCID25235123

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClCCl
溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

In analogy to example 13, step 2, isobutyl-[5-(3-methanesulfonyl-phenyl)-thiophen-2-ylmethyl]-amine (example 15, step 2) was reacted with 3-chloro-2-fluorophenylsulfonyl chloride and N,N-diisopropyl ethyl amine in dichloromethane to give 3-chloro-2-fluoro-N-isobutyl-N-[5-(3-methanesulfonyl-phenyl)-thiophen-2-ylmethyl]-benzenesulfonamide as a colorless oil. MS: 532.7 ([M+NH4]+)