Trifluoroacetic acid → HCID 15175833, compound

HRID 1666208Notes

Reaction equation

HRID 1666208 reaction equation
C(OC([NH:8][C@H:9]([C:17]([N:19]([CH3:25])[CH2:20][C:21](OC)=[O:22])=[O:18])[CH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)=O)(C)(C)C.FC(F)(F)C(O)=O.C(N(CC)CC)C>CO>[CH2:10]([CH:9]1[C:17](=[O:18])[N:19]([CH3:25])[CH2:20][C:21](=[O:22])[NH:8]1)[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

Participants

5

Reactant 3

HCID 6422Trifluoroacetic acidHCID 8471TriethylamineHCID 67445007HCID 67445007, compound

Product 1

HCID 15175833HCID 15175833, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The compound obtained in Step (i) was treated with trifluoroacetic acid (30 ml), and then the resultant was heated under reflux in methanol in the presence of triethylamine to give the subtitle compound.

Workup

  1. temperaturethe resultant was heated

Sources & evidence

ORD record
ord-9ffcc63ee46e41c8831297297d5795d1
Source dataset
uspto-grants-2011_10
Patent number
US08044056B2

Reaction notes

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