Hydrochloric Acid → HCID 59150525, compound

HRID 1668589Notes

Reaction equation

HRID 1668589 reaction equation
CO[CH:3](OC)[CH2:4][NH:5][C:6](=[O:17])[CH2:7][C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([O:14][CH3:15])[C:9]=1[CH3:16].Cl>C(O)(=O)C>[CH3:15][O:14][C:10]1[CH:11]=[CH:12][C:13]2[CH:3]=[CH:4][NH:5][C:6](=[O:17])[CH2:7][C:8]=2[C:9]=1[CH3:16]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 59150524HCID 59150524, compound

Product 1

HCID 59150525HCID 59150525, compoundYield 62%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A solution of N-(2,2-dimethoxy-ethyl)-2-(3-methoxy-2-methyl-phenyl)-acetamide (23 g) in a mixture of acetic acid (40 ml) and conc. HCl (40 ml) was stirred at room temperature for 24 hours. Ice was added with vigorous stirring and the obtained precipitated was filtered (10.9 g, 62% yield).

Workup

  1. additionIce was added
  2. stirringwith vigorous stirring
  3. customthe obtained precipitated
  4. filtrationwas filtered (10.9 g, 62% yield)

Sources & evidence

ORD record
ord-74ac2c9c7c264d6cb6fc736daf790d28
Source dataset
uspto-grants-2011_08
Patent number
US07989444B2

Reaction notes

Loading…