Hydrochloric Acid → Diethylaminoethylaniline dihydrochloride

HRID 1670856Notes

Reaction equation

HRID 1670856 reaction equation
[CH2:1]([N:3]([CH2:6][CH2:7][NH:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1)[CH2:4][CH3:5])[CH3:2].[ClH:15]>CO.O1CCOCC1>[ClH:15].[ClH:15].[CH2:1]([N:3]([CH2:6][CH2:7][NH:8][C:9]1[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=1)[CH2:4][CH3:5])[CH3:2]

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 742711,2-Ethanediamine, N1,N1-diethyl-N2-phenyl-

Product 1

HCID 56729931Diethylaminoethylaniline dihydrochloride

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 312751,4-DioxaneSolvent

Procedure

To a round bottom flask, 62.6 mg (0.153 mmol) of 5 was dissolved in 1 mL of methanol. To this solution 1 mL of 4 N HCl in dioxane was added slowly, stirred at room temperature for 1 h and concentrated to afford a quantitative amount (52.7 mg) of 6.

Workup

  1. concentrationconcentrated

Sources & evidence

ORD record
ord-82f9d4801e924a9eb76a9a08a30de5b8
Source dataset
uspto-grants-2011_08
Patent number
US07994172B2

Reaction notes

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