Methanol → 3-{4-[2-(2,2,2-Trifluoroethoxy)-3-tert-butyl-5-methylphenyl]benzo[b]thien-2-yl}but-2-enoic acid
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4]([CH:5]=[C:6]([CH3:7])[c:8]1[cH:9][c:10]2[c:11]([s:12]1)[cH:13][cH:14][cH:15][c:16]2-[c:17]1[c:18]([O:28][CH2:29][C:30]([F:31])([F:32])[F:33])[c:19]([C:24]([CH3:25])([CH3:26])[CH3:27])[cH:20][c:21]([CH3:23])[cH:22]1)=[O:34].[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[CH3:42][OH:43].[Li+:41].[OH-:40]>>[O:3]=[C:4]([CH:5]=[C:6]([CH3:7])[c:8]1[cH:9][c:10]2[c:11]([s:12]1)[cH:13][cH:14][cH:15][c:16]2-[c:17]1[c:18]([O:28][CH2:29][C:30]([F:31])([F:32])[F:33])[c:19]([C:24]([CH3:25])([CH3:26])[CH3:27])[cH:20][c:21]([CH3:23])[cH:22]1)[OH:34]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-f06b4e6f5e3b4213888a80bb90571676
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…