Dimethylformamide dimethyl acetal → HCID 54387791, compound

HRID 1672087Notes

Reaction equation

[NH2:1][C:2]1[NH:3][CH:4]=[CH:5][N:6]=1.CO[CH:9](OC)[N:10]([CH3:12])[CH3:11]>>[CH3:9][N:10]([CH:12]=[N:1][C:2]1[NH:3][CH:4]=[CH:5][N:6]=1)[CH3:11]

Participants

Reactant 2

HCID 78373Dimethylformamide dimethyl acetal

HCID 821402-Aminoimidazole

Product 1

HCID 54387791HCID 54387791, compound

Procedure

To the crude 2-aminoimidazole (18.2 g) was added dimethylformamide dimethyl acetal (145 mL) (Aldrich) and stirred at room temperature overnight. The reagent was removed in vacuo to give crude 2 (32.66 g) which was taken on to the next step (tritylation) without further purification.

Workup

customThe reagent was removed in vacuo

Sources & evidence

ORD record: ord-3a17c757b1bc4c66ae78780072034265
Source dataset: uspto-grants-2011_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07998462B2

Reaction notes

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