Acetic Anhydride → 3-Methyl-2-oxaspiro[4.5]decan-1-yl acetate

HRID 1672110노트

반응식

HRID 1672110 반응식
[CH3:1][CH:2]1[CH2:6][C:5]2([CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]2)[CH:4]([OH:12])[O:3]1.[C:13](OC(=O)C)(=[O:15])[CH3:14]>N1C=CC=CC=1>[C:13]([O:12][CH:4]1[C:5]2([CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]2)[CH2:6][CH:2]([CH3:1])[O:3]1)(=[O:15])[CH3:14]

참가 물질

4

반응물 2

HCID 7918Acetic AnhydrideHCID 596492103-Methyl-2-oxaspiro[4.5]decan-1-ol

생성물 1

HCID 596492113-Methyl-2-oxaspiro[4.5]decan-1-yl acetate

시약·촉매·용매 1

HCID 1049Pyridine용매

반응 조건

온도
50 °C

실험 절차

A mixture of 11 g of 3-methyl-2-oxaspiro[4.5]decan-1-ol, 7.7 g of pyridine and 9.2 g of acetic anhydride was heated at 50° C. for 12 hours. The reaction mixture was concentrated. The concentrate was purified by distillation, obtaining 13 g (yield 960) of the target compound, 3-methyl-2-oxaspiro[4.5]decan-1-yl acetate.

후처리

  1. concentrationThe reaction mixture was concentrated
  2. distillationThe concentrate was purified by distillation
  3. customobtaining

출처 및 근거

ORD 기록
ord-6af6488394e749faadde0d6633899e39
출처 데이터셋
uspto-grants-2011_08
특허 번호
US07998657B2

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