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HRID1672379

反应详情

EQUATION

反应方程式

HRID 1672379 的结构方程式

REACTANTS

反应物

3
结构：CCN(C(C)C)C(C)C
HCID81531

Diisopropylethylamine

C8H19N

结构：O=S(=O)(Cl)c1ccc(OC(F)F)cc1
HCID2778223

4-(Difluoromethoxy)benzenesulfonyl chloride

C7H5ClF2O3S

结构：O=C1N(c2ccccc2Cl)CCC12CCCN2
HCID58948331

未命名化合物

PRODUCTS

生成物

1
结构：O=C1N(c2ccccc2Cl)CCC12CCCN2S(=O)(=O)c1ccc(OC(F)F)cc1
HCID67354943

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClCCl
溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

7-(2-Chlorophenyl)-1,7-diazaspiro[4.4]nonan-6-one (20 mg, 0.00008 mol) was dissolved in DCM. To this solution was added N,N-diisopropylethylamine (DIPEA) (42 μL, 0.00024 mol) and 4-(difluoromethoxy)benzenesulfonyl chloride (21 mg, 0.000088 mol) at 0° C. The solution was allowed to gradually warm to RT while stirring for 18 h. LC-MS: 457.1 (M+1H)+.