Bicarbonate Ion → 7-(Benzyloxy)-4-chloro-6-methoxyquinoline-3-carbonitrile

HRID 167328Notes

Reaction equation

HRID 167328 reaction equation
[C:35](=[O:36])([OH:37])[O-:38].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([O:22][CH3:23])[cH:11][c:12]2[c:13]([OH:21])[c:14]([C:19]#[N:20])[cH:15][n:16][c:17]2[cH:18]1.[CH2:40]([Cl:41])[Cl:42].[CH3:30][N:31]([CH3:32])[CH:33]=[O:34].[Cl:24][C:25]([C:26]([Cl:27])=[O:28])=[O:29].[Na+:39]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[c:10]([O:22][CH3:23])[cH:11][c:12]2[c:13]([Cl:24])[c:14]([C:19]#[N:20])[cH:15][n:16][c:17]2[cH:18]1

Participants

7

Reactant 6

HCID 769Bicarbonate IonHCID 923Sodium ionHCID 6228DimethylformamideHCID 6344DichloromethaneHCID 65578Oxalyl chlorideHCID 178486760HCID 178486760, compound

Product 1

HCID 224666467-(Benzyloxy)-4-chloro-6-methoxyquinoline-3-carbonitrile

Sources & evidence

ORD record
ord-f8b96e467f3743e4bdf40382fae2e273
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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