HCID 67344515, compound → HCID 67344440, compound

HRID 1673343Notes

Reaction equation

HRID 1673343 reaction equation
[N+:1]([C:4]1[CH:12]=[C:11]([CH:13]=[CH:14][CH2:15][CH2:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[CH:10]=[CH:9][C:5]=1[C:6]([O-:8])=[O:7])([O-])=O>[C].[Pd].C(OCC)(=O)C>[NH2:1][C:4]1[CH:12]=[C:11]([CH2:13][CH2:14][CH2:15][CH2:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[CH:10]=[CH:9][C:5]=1[C:6]([O:8][C:5]([CH3:9])([CH3:6])[CH3:4])=[O:7]

Participants

4

Reactant 1

HCID 67344515HCID 67344515, compound

Product 1

HCID 67344440HCID 67344440, compoundYield 208.1%

Reagents, catalysts & solvents 2

HCID 178418390HCID 178418390, compoundCatalystHCID 8857Ethyl AcetateSolvent

Procedure

70 mg of 5% palladium-carbon was added to 4 mL of ethyl acetate solution containing 0.35 g of 2-nitro-4-(4-phenyl-1-butenyl)benzoate and stirred under hydrogen atmosphere at room temperature for 8 hours. Insoluble were removed by filtration, and the solvent was evaporated under reduced pressure to obtain 0.40 g of tert-butyl 2-amino-4-(4-phenylbutyl)benzoate as yellow oil.

Workup

  1. customInsoluble were removed by filtration
  2. customthe solvent was evaporated under reduced pressure

Sources & evidence

ORD record
ord-e350b239f3d2456ea8269349b57acf67
Source dataset
uspto-grants-2011_08
Patent number
US07999132B2

Reaction notes

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