Methanol → HCID 57879594, compound

HRID 1673531Notes

Reaction equation

HRID 1673531 reaction equation
C(=O)([O-])[O-].[K+].[K+].CO.C([O:12][C:13]1[CH:38]=[CH:37][C:16]([C:17]([NH:19][C:20]2[CH:28]=[C:27]([CH2:29][CH2:30][C:31]3[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=3)[CH:26]=[CH:25][C:21]=2[C:22]([OH:24])=[O:23])=[O:18])=[CH:15][CH:14]=1)(=O)C>O1CCCC1>[OH:12][C:13]1[CH:14]=[CH:15][C:16]([C:17]([NH:19][C:20]2[CH:28]=[C:27]([CH2:29][CH2:30][C:31]3[CH:32]=[CH:33][CH:34]=[CH:35][CH:36]=3)[CH:26]=[CH:25][C:21]=2[C:22]([OH:24])=[O:23])=[O:18])=[CH:37][CH:38]=1

Participants

5

Reactant 3

HCID 887MethanolHCID 11430Potassium CarbonateHCID 57879505HCID 57879505, compound

Product 1

HCID 57879594HCID 57879594, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

10 mg of potassium carbonate were added to a mixed solution of 1.0 mL of methanol and 1.0 mL of tetrahydrofuran containing 20 mg of 2-(4-acetoxybenzamido)-4-phenethylbenzoic acid and stirred at room temperature for 3 hours. After insoluble were removed by filtration, 3.0 mL of 10% citric acid aqueous solution was added and a solid substance was separated by filtration to obtain 15 mg of 2-(4-hydroxybenzamido)-4-phenethylbenzoic acid as white solid.

Workup

  1. customAfter insoluble were removed by filtration, 3.0 mL of 10% citric acid aqueous solution
  2. additionwas added
  3. customa solid substance was separated by filtration

Sources & evidence

ORD record
ord-d5390fcbfe1f46929166788554cb9437
Source dataset
uspto-grants-2011_08
Patent number
US07999132B2

Reaction notes

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