Ammonium → tert-Butyl 4-(6-bromopyridin-2-yl)-4-hydroxypiperidine-1-carboxylate
Reaction equation
[Br:1][c:2]1[n:3][c:4]([Br:8])[cH:5][cH:6][cH:7]1.[CH2:9]([Li:10])[CH2:11][CH2:12][CH3:13].[Cl-:28].[Cl:30][CH2:31][Cl:32].[NH4+:29].[O:14]=[C:15]1[CH2:16][CH2:17][N:18]([C:21](=[O:22])[O:23][C:24]([CH3:25])([CH3:26])[CH3:27])[CH2:19][CH2:20]1>>[c:2]1([C:15]2([OH:14])[CH2:16][CH2:17][N:18]([C:21](=[O:22])[O:23][C:24]([CH3:25])([CH3:26])[CH3:27])[CH2:19][CH2:20]2)[n:3][c:4]([Br:8])[cH:5][cH:6][cH:7]1Participants
7
Sources & evidence
- ORD record
- ord-9d8770c468554836a32a7a430b04ec7a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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